It is our great honor to welcome you to the second International Conference of Mathematics and Applications, hosted by the King Khalid University, Abha, Saudi Arabia, 17-18 February 2020.The Conference provides a forum to a diverse group area include, but not limited to differential equations, mathematical biology, computational mathematics, analysis, statistics, big data, algebra, and optimization. The conference aims to bring together researchers from a variety of disciplines which impact mathematical analysis and applications. It will gather PhD students and master’s students.